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Workshops


Understanding the biological function of a protein using structural bioinformatics

Leader: Anna Reymer

Abstract: Structural bioinformatics studies molecular structures and interactions to explain the function of a biological molecule in question, and when necessary find a way to block this function for medicinal purposes. In this workshop, we will combine homology modeling to create a model of a protein, and molecular docking to study interactions of the protein with a set of small ligands, potentially pharmacologically potent. NOTE: Bring your own laptop and have USCF Chimera installed!

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Wait a minute! – On annotation errors and how to spot them

Leader: Johan Bengtsson-Palme

Abstract: Bioinformatic approaches for functional predictions rely upon correctly annotated database sequences. However, the assumption that the information in biological databases can be trusted is only sometimes true. The presence of inaccurately annotated or otherwise poorly described sequences introduces noise and bias to biological analyses and in the worst cases lead us do draw totally wrong conclusions. In this workshop, we will look at some things to be suspicious about in bioinformatic results and discuss strategies to deal with poorly annotated reference sequences.
 

Page Manager: Sanna Abrahamsson|Last update: 10/17/2019
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